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In fact, a new vaginal yeast infection can be a side effect of metronidazole treatment. Call your doctor if you develop signs of a fungal Ask your care team if you should avoid alcohol. Many nonprescription cough and cold products contain alcohol. Metronidazole can cause an unpleasant reaction UTI is an abbreviation for urinary tract infection. Although there is no scientific basis that metronidazole can cause UTI, one of the severe side effects is wixela inhub coupon urine), diabetes, kidney, liver and heart problems. Drug-Drug Antibiotics can alter the useful bacteria in the stomach, which help in digestion. Genitourinary side effects have included vaginal fungal infections (1%) and vulvovaginal infections (1.3%). Hematuria, urinary tract infections, metrorrhagia, dysuria, urinary frequency, nocturia, penile infection, proteinuria, vaginitis, and vaginal pain have been reported in less than 1% of patients. Change in quantity of urine has been reported. Metronidazole (Flagyl) is typically well tolerated, with the most common side effects being headache, nausea, and diarrhea. It can also leave a metallic taste in your mouth. Rare but serious side effects like confusion, trouble speaking, and nerve damage are more likely when you take metronidazole for 2 weeks or longer.